Obinutuzumab (GA101) is a humanized, monoclonal type II CD20 antibody modified by glycoengineering. The glycoengineered Fc portion enhances ... ... <看更多>
「ga101 antibody」的推薦目錄：
ga101 antibody 在 A Review of Obinutuzumab (GA101), a Novel Type II Anti- ... 的相關結果
Abstract. Obinutuzumab (GA101) is a novel, type II, glycoengineered, humanized anti-CD20 monoclonal antibody that has been developed to address ... ... <看更多>
ga101 antibody 在 Novel type II anti-CD20 monoclonal antibody (GA101) evokes ... 的相關結果
In this study, we confirm that GA101 is a type II anti-CD20 mAb that in contrast to rituximab induces high levels of PCD in B-lymphoma cell lines, and extend ... ... <看更多>
ga101 antibody 在 Preclinical Activity of the Type II CD20 Antibody GA101 ... 的相關結果
Obinutuzumab (GA101) is a novel type II, humanized, CD20 mAb that has been glycoengineered to reduce core fucosylation, conferring enhanced affinity for the ... ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) is highly effective against chronic ... 的相關結果
The anti-CD20 monoclonal antibody rituximab has revolutionized the management of B-cell non-Hodgkin's lymphoma and chronic lymphocytic leukemia ... ... <看更多>
ga101 antibody 在 The Type II Anti‐CD20 Antibody Obinutuzumab (GA101) Is ... 的相關結果
The Type II Anti-CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus ... ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) | CD20 的相關結果
NCT Number Sponsor Start Date Phase
NCT02612311 TG Therapeutics, Inc. November 19, 2015 Phase 3
NCT05376319 Mayo Clinic June 2023 Phase 2
NCT02983617 Gilead Sciences|German CLL Study Group April 6, 2017 Phase 2 ... <看更多>
ga101 antibody 在 study protocol for a phase II/III randomised controlled trial 的相關結果
Obinutuzumab (GA-101) is a novel monoclonal antibody and has been shown to have greater efficacy in CLL than previous anti-CD20 antibodies [5, 6] ... ... <看更多>
ga101 antibody 在 Combination of the Glycoengineered Type II CD20 ... 的相關結果
Obinutuzumab (GA101) is a novel glycoengineered type II, anti-CD20 monoclonal antibody that strongly induces direct cell death. As a result of ... ... <看更多>
ga101 antibody 在 Rationale for optimal obinutuzumab/GA101 dosing ... 的相關結果
Obinutuzumab (GA101) is a type II, glycoengineered anti-CD20 monoclonal antibody for the treatment of hematologic malignancies. ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) vs. rituximab significantly ... 的相關結果
Obinutuzumab (GA101) vs. rituximab significantly enhances cell death, antibody-dependent cytotoxicity and improves overall survival against ... ... <看更多>
ga101 antibody 在 ISRCTN64035629: GA101 (obinutuzumab) monoclonal ... 的相關結果
Study information. Scientific title. GA101 (obinutuzumab) monocLonal Antibody as Consolidation Therapy In CLL: a randomised controlled trial. Acronym. GALACTIC ... ... <看更多>
ga101 antibody 在 Obinutuzumab (anti-CD20) | CD markers inhibitor 的相關結果
GA101 is the first Fc-engineered, type II humanized IgG1 antibody against CD20. Relative to rituximab, GA101 has increased direct and immune effector cell- ... ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) in Patients With Relapsed/ ... 的相關結果
This antibody has become a key component of standard therapy for non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia and of maintenance ... ... <看更多>
ga101 antibody 在 Mechanism of Action of Type II, Glycoengineered, Anti-CD20 ... 的相關結果
... Anti-CD20 Monoclonal Antibody GA101 in B-Chronic Lymphocytic Leukemia ... GA101, but not rituximab, also mediated significant NK cell degranulation in ... ... <看更多>
ga101 antibody 在 Combination therapy of a type ii anti-cd20 antibody with ... 的相關結果
Antitumor activity of combined treatment of a type II anti-CD20 antibody (GA101 antibody, in this case, obinutuzumab) with a Bcl-2 inhibitor (ABT-199, a.k.a. ... ... <看更多>
ga101 antibody 在 OBINUTUZUMAB 的相關結果
CD20 monoclonal antibody (MAb), to conventional chemotherapy, ... gen B1, Leu-16, Bp35)], humanized monoclonal antibody, GA101; γ1 heavy chain (1-448) ... ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) – a different anti-CD20 antibody ... 的相關結果
The anti-CD20 monoclonal antibody (mAb) rituximab has revolutionised treatment approaches and improved outcome for patients in a wide range ... ... <看更多>
ga101 antibody 在 The type II anti-CD20 antibody GA101 mediates superior ... 的相關結果
Download scientific diagram | The type II anti-CD20 antibody GA101 mediates superior direct cell death induction in normal and malignant B cells. ... <看更多>
ga101 antibody 在 A Glycoengineered Type II CD20 Antibody 的相關結果
Obinutuzumab (GA101) for the Treatment of Chronic Lymphocytic Leukemia and Other B-Cell Non-Hodgkin's Lymphomas: A Glycoengineered Type II CD20 ... ... <看更多>
ga101 antibody 在 Obinutuzumab (afutuzumab; GA101) | CAS 949142-50-1 的相關結果
Obinutuzumab (GA101) is a fully humanized monoclonal antibody that binds to an epitope on CD20. Obinutuzumab binds to CD20 on B cells and causes these cells ... ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101) significantly improved progression ... 的相關結果
GA101 has been specifically designed as the first glycoengineered, type 2 anti-CD20 monoclonal antibody in development for B cell malignancies. ... <看更多>
ga101 antibody 在 A Review of Obinutuzumab (GA101), a Novel ... - Adis Journals 的相關結果
A Review of Obinutuzumab (GA101), a Novel Type II Anti-CD20 Monoclonal Antibody, for the Treatment of Patients with B-Cell Malignancies. ... <看更多>
ga101 antibody 在 GA101 (obinutuzumab) monoclonal antibody as ... 的相關結果
GA101 (obinutuzumab) monoclonal antibody as consolidation therapy In CLL. How this CENTRAL record is used in Cochrane Reviews. ... <看更多>
ga101 antibody 在 Obinutuzumab (GA101), a New Generation Rituximab 的相關結果
Obinutuzumab (GA101) is a newer generation anti-CD20 antibody that has undergone significant engineering to capitalize on new knowledge. In ... ... <看更多>
ga101 antibody 在 Phase II Randomized Trial Comparing GA101 and ... 的相關結果
GA101 is an anti-CD20 humanized and glyco-engineered monoclonal antibody. GA101 has been shown to have increased antibody-dependent cellular cytotoxicity ... ... <看更多>
ga101 antibody 在 Preclinical studies on the mechanism of action and the anti ... 的相關結果
As expected for a Type II antibody, GA101 appears not to act through CDC and is more ... of these proteins in the apoptotic signalling of anti-CD20 antibodies. ... <看更多>
ga101 antibody 在 Obinutuzumab in hematologic malignancies 的相關結果
The routine use of anti-CD20 monoclonal antibodies (mAbs) has improved patient ... antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab. ... <看更多>
ga101 antibody 在 Unexpected cross-reactivity of anti-cathepsin B antibodies ... 的相關結果
anism of action of anti-CD20 monoclonal antibody GA101. ... Cell killing by GA101 (obinutuzumab, Gazyva) may be cathepsin-independent. ... <看更多>
ga101 antibody 在 ( 12 ) United States Patent 的相關結果
the present invention is a GA101 antibody . obinutuzumab ) with a Bcl - 2 inhibitor ( ABT - 199 , a.k.a.. 65. Page 10 ... ... <看更多>
ga101 antibody 在 Unexpected cross-reactivity of anti-cathepsin B antibodies ... 的相關結果
... of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101. ... <看更多>
ga101 antibody 在 Obinutuzumab|Cas# 949142-50-1 的相關結果
Obinutuzumab (GA101) a novel glycoengineered Type II CD20 humanized IgG1 monoclonal antibody in development for non-Hodgkin lymphoma. ... <看更多>
ga101 antibody 在 Mouse Anti-MS4A1 Recombinant Antibody (clone GA101) 的相關結果
Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with ... ... <看更多>
ga101 antibody 在 125486Orig1s000 - Accessdata.fda.gov 的相關結果
Preclinical activity of the Type II CD20 antibody GA101 (Obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft ... ... <看更多>
ga101 antibody 在 A Glycoengineered Type II CD20 Antibody 的相關結果
Obinutuzumab (GA101) for the Treatment of Chronic Lymphocytic Leukemia and Other B-Cell Non-Hodgkin's Lymphomas: A Glycoengineered Type II CD20 Antibody. ... <看更多>
ga101 antibody 在 Press Releases │ NIPPON SHINYAKU CO., LTD. 的相關結果
GA101 is a glycoengineered type II anti-CD20 monoclonal antibody created by GlycArt AG and is a compound that selectively targets the CD20 ... ... <看更多>
ga101 antibody 在 Proposed Mechanism of Action in First-Line Follicular ... 的相關結果
GAZYVA, a type II antibody, directly activates intracellular death signaling ... Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) ... ... <看更多>
ga101 antibody 在 The Potential Cost-Effectiveness of Obinutuzumab (Ga101) ... 的相關結果
Obinutuzumab is the first, glycoengineered type II antibody demonstrating increased Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and direct cell ... ... <看更多>
ga101 antibody 在 Paper: CC-122 Exhibits Potent Anti-Lymphoma Activity in ... 的相關結果
... Cell Autonomous and Antibody Dependent Cell Mediated Cytotoxicity ... CC-122 with anti-CD20 monoclonal antibody obinutuzumab (GA101) in ... ... <看更多>
ga101 antibody 在 CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) ... 的相關結果
CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) ... <看更多>
ga101 antibody 在 Glycoengineering of Therapeutic Antibodies - Thieme Connect 的相關結果
Obinutuzumab (GA101, RG7159) is a type II, anti-CD20. GlycoMab monoclonal antibody that was designed to medi- ate enhanced direct and immune effector ... ... <看更多>
ga101 antibody 在 Novel type II anti-CD20 monoclonal ... - Research Explorer 的相關結果
Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell ... ... <看更多>
ga101 antibody 在 Roche's blood cancer antibody outperforms MabThera 的相關結果
GA101 (obinutuzumab) more effective than MabThera/Rituxan in a head-to-head study in patients with non-Hodgkin's lymphoma - PMLiVE. ... <看更多>
ga101 antibody 在 Biogen Idec Elects to Participate with Genentech in the ... 的相關結果
GA101 is a novel humanized anti-CD20 monoclonal antibody engineered to increase both direct- and immune-mediated target cell death for the ... ... <看更多>
ga101 antibody 在 Obinutuzumab 的相關結果
Obinutuzumab, sold under the brand name Gazyva among others, is a humanized anti-CD20 monoclonal antibody, originated by GlycArt ... in Zurich to develop afucosylated monoclonal antibodies; GA101 was one of ... ... <看更多>
ga101 antibody 在 Increasing the efficacy of CD20 antibody therapy through ... 的相關結果
Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector ... ... <看更多>
ga101 antibody 在 Clinical role of obinutuzumab in the treatment of naive ... 的相關結果
Obinutuzumab (GA101) is a novel humanized Type II anti-CD20 monoclonal antibody that has been investigated and compared to rituximab. Here, we ... ... <看更多>
ga101 antibody 在 Anti-hCD20 hIgG1 | Obinutuzumab-based 的相關結果
InvivoGen's Anti-hCD20-Ga-hIgG1 is a monoclonal antibody targeting human ... of Obinutuzumab (formerly named Afutuzumab or GA101) which targets the human ... ... <看更多>
ga101 antibody 在 3PP3: Epitope characterization and crystal structure ... 的相關結果
Rituximab, a monoclonal antibody targeting CD20, has improved the treatment of malignant lymphomas. Therapeutic CD20 antibodies are classified ... ... <看更多>
ga101 antibody 在 and 124I- labeled obinutuzumab antibody fragments 的相關結果
labeled GA101 antibody fragments to assess internalization of CD20/antibody complexes in vivo by comparing quantitative PET images over time, ... ... <看更多>
ga101 antibody 在 Cd20 monoclonal antibody 的相關結果
GA101, also known as obinutuzumab or Gazyva (Gazyvaro), is a glycoengineered type II humanized antibody that targets the CD20 antigen ... ... <看更多>
ga101 antibody 在 Obinutuzumab plus Chlorambucil in Patients with CLL and ... 的相關結果
Background The monoclonal anti-CD20 antibody rituximab, ... glycoengineered antibody obinutuzumab (also known as GA101) as compared with ... ... <看更多>
ga101 antibody 在 obinutuzumab - My Cancer Genome 的相關結果
Obinutuzumab, a third generation type II anti-CD20 antibody, selectivity binds to ... ga 101, obinutuzumab (substance), afutuzumab, ga-101, ga101 antibody, ... ... <看更多>
ga101 antibody 在 Anti-CD20 [RA2 (Caninized)] 的相關結果
Recombinant anti-Dog CD20 (B-lymphocyte antigen CD20) antibody. ... RA2 is a caninised antibody derived from GA101 and capable of binding canine CD20, ... ... <看更多>
ga101 antibody 在 Obinutuzumab (anti-CD20) | CD markers 阻害剤 的相關結果
Obinutuzumab (Gazyva, GA101, Gazyvaro, Afutuzumab) (anti-CD20) is a novel, type II, glycoengineered, humanized anti-CD20 monoclonal antibody that has been ... ... <看更多>
ga101 antibody 在 Advances in antibody therapy for B cell lymphoma 的相關結果
Obinutuzumab (GA101) for the treatment of chronic lymphocytic leukemia and other B-cell non-Hodgkin's lymphomas: a glycoengineered type II CD20 antibody. Oncol ... ... <看更多>
ga101 antibody 在 Use of GA101 and Clb preferable to rituximab in elderly or ... 的相關結果
Dr Goede talks to ecancertv at BSH 2014 about his work which compares the use of antibodies GA101 and Clb to the use of rituximab plus Clb ... ... <看更多>
ga101 antibody 在 Obinutuzumab (anti-CD20) 的相關結果
InformationObinutuzumab (anti-CD20) (Gazyva, GA101, Gazyvaro, Afutuzumab) is a novel, type II, glycoengineered, humanized anti-CD20 monoclonal antibody that ... ... <看更多>
ga101 antibody 在 Handbook of Therapeutic Antibodies - 第 xii 頁 - Google 圖書結果 的相關結果
... utilized CD20-directed antibodies in chronic lymphocytic leukemia cells ... action and the anti-lymphoma activity of the novel anti-CD20 antibody GA101. ... <看更多>
ga101 antibody 在 CD20 Monoclonal Antibodies—Advances in Research and ... 的相關結果
According to recent research published in the journal Molecular Cancer Therapeutics, “GA101 is a novel glycoengineered Type II CD20 monoclonal antibody. ... <看更多>
ga101 antibody 在 Frontiers in Clinical Drug Research: Hematology 的相關結果
Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and ... Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic ... ... <看更多>
ga101 antibody 在 Transcript of Investor Presentation held on March 2, 2009 的相關結果
... Xolair, Lucentis, lytics, GA101, HER2-positive franchise, and TNKase; ... An antibody called IgG, that particular subtype of antibody is ... ... <看更多>
ga101 antibody 在 Aggressive Lymphomas - 第 323 頁 - Google 圖書結果 的相關結果
Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with ... ... <看更多>
ga101 antibody 在 Carbohydrate Chemistry - 第 38 卷 - 第 108 頁 - Google 圖書結果 的相關結果
ADCC-enhanced antibodies are expected to treat new patient subpopulations ... cell line to produce the GA101 antibody currently in clinical trials [115]. ... <看更多>
ga101 antibody 在 無題 的相關結果
Ga101 antibody titers. Valverde inmobiliaria peru. 80 billion neurons diagram. Radisson blu paschim vihar banquet coupons. Santa's email address 2012 ... ... <看更多>
ga101 antibody 在 Obinutuzumab 的相關結果
Dec 21, 2016 · Obinutuzumab (GA101) is a novel, type II, glycoengineered, humanized anti-CD20 monoclonal antibody that has been developed to address the ... ... <看更多>
ga101 antibody 在 Cymbalta 60 Mg Para Que Sirve - MANOBRA DIGITAL 的相關結果
... Remicade -the first time for such antibody-based medicines how much does. ... cvs The success of drugs such as Kadycla and Perjeta, as well asits GA101. ... <看更多>
ga101 antibody 在 A Review of Obinutuzumab (GA101), a Novel Type II Anti- ... 的相關結果
Obinutuzumab (GA101) is a novel, type II, glycoengineered, humanized anti-CD20 monoclonal antibody that has been developed to address the need for new ... ... <看更多>